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OSU-T315

Glpbio

Catalog No：GC36821-10mM (in 1mL DMSO) CAS No.：2070015-22-2 MDLNo： Brand:Glpbio purity： 特性： Purpose:OSU-T315 是整联蛋白连接激酶 (ILK) 的抑制剂 (IC50=0.6 μM), 通过去磷酸化 AKT-Ser473 和其他 ILK 靶标 (GSK-3β和肌球蛋白轻链) 抑制 PI3K/AKT 信号传导。OSU-T315 阻止 AKT 转位到脂筏消除 AKT 的活化，并以 ILK 非依赖性方式触发 Caspase 依赖性细胞凋亡 (Apoptosis)。OSU-T315 通过自噬 (Autophagy) 和凋亡 (Apoptosis) 导致细胞死亡。DMSO: ≥ 50 mg/mL (93.70 mM); H2O: < 0.1 mg/mL (insoluble)

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Product Overview

Product Name	OSU-T315
CAS	2070015-22-2
Formula	C₃₀H₃₀F₃N₅O
MW	533.59
Storage condition	Store at -20°C

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